Hope of a Cure for Sickle Cell

In the midst of the pandemic and protests and political mayhem, the grim news can be overwhelming. But there’s wonderful news, too. Remember the gene-editing technique, CRISPR? A year after gene-editing, a woman with severe sickle cell disease feels great. This success signals hope of a cure for Sickle Cell disease. Sickle Cell Disease According to the Centers for Disease Control, Sickle Cell Disease (SCD) is a group of inherited red blood cell disorders. A healthy red blood cell is round. It travels through our blood vessels, even the tiny capillaries, and delivers oxygen to all parts of the body. When a person has SCD, their red blood cells become hard and sticky and shaped like a farm tool called the sickle. These abnormal cells get stuck in small blood vessels. This clogs blood flow. It can cause mild-to-severe pain and many serious problems like strokes. These cells also die early, causing anemia. There are three common types of Sickle Cell and three rare types. Some people carry the trait (they have half the genetic material that causes the disease). If two people with the trait have a child, they have a 50% chance of passing on the trait and […]